DivcoWest Tops Off Sanofi’s U.S. Research Headquarters at Cambridge Crossing


Cambridge, MA, (December 29, 2020) – DivcoWest, joined by construction partners John Moriarty and Associates and Consigli Construction, recently celebrated the topping off of two major parcels, 350 Water Street and 450 Water Street, in Cambridge Crossing (CX), the new 45-acre neighborhood under construction at the intersection of Cambridge, Somerville, and Boston. The brand-new state-of-the-art buildings will be home to global biopharmaceutical leader Sanofi and will be the company’s U.S. research headquarters with a consolidated workforce of nearly 3,000 employees.

“The topping off milestones of these two buildings are a huge achievement at Cambridge Crossing and are a testament to the hard work and dedication of the entire team. These milestones signify tremendous progress at the site during what has been an unprecedented year,” said Mark Roopenian, Managing Director at DivcoWest. “Now more than ever, we are committed to our goal of creating an interconnected ecosystem at CX in which innovative leaders in science and technology, like Sanofi, can create cutting-edge solutions to major healthcare issues impacting the world. This is a tremendous way to cap off 2020 and we are grateful to all the men and women on the site who’ve helped get us here.”

Designed by Perkins & Will, 350 Water Street will be a 501,000 SF state-of-the-art lab building  and 450 Water Street will be a 405,000 SF contemporary office building, designed by NBBJ. The buildings are designed with a focus on sustainability and will incorporate architectural elements and infrastructure that minimizes their impact on the environment such as solar shading fins to reduce heat gain and energy usage and a highly efficient chilled beam system. LEED Gold certifications are being sought at both buildings as well as Wired Score and WELL certifications.

Currently, there are as many as 350 workers every day across Sanofi’s two sites, using over 13,000 tons of structural steel combined. In September 2019, CX made history with its concrete pour at 350 Water Street – it was the largest continuous pour ever completed in the greater Boston region and included more than 800 truck loads of concrete.

Approximately 1.7 million square-feet of commercial space is leased and preleased at CX. In addition to Sanofi, Bristol Myers Squibb has signed a lease for 360,000 SF at 250 Water Street joining Philips North America and Cerevel Therapeutics, which currently occupy 435,000 SF at 222 Jacobs Street.  Remaining science and technology space at CX includes 110,000 SF at 250 Water Street and 600,000 SF in two future buildings. CX’s first residential building broke ground in early 2020 and its first retail building, The Shed, recently opened with Chef Will Gilson’s restaurants The Lexington and Café Beatrice.

With close proximity to Kendall Square, MIT and Harvard, the life science community at CX is a thoughtfully designed, vibrant neighborhood that inspires collaboration, innovation and connection. Once complete, the community will provide a one-of-a-kind place for employees, residents and neighbors connected to two MBTA stations and surrounded by 11 acres of open space, an eclectic food scene, neighborhood retail, and more than 2,400 residences in addition to the already 2500 residences in close proximity.

For more information and updates on CX, visit, or follow along on Instagram, Facebook, LinkedIn, and Twitter.


About Cambridge Crossing
Cambridge Crossing (CX) is a 43-acre, 4.5 million-square-foot transit-oriented neighborhood located at the intersection of Cambridge, Somerville, and Boston. Once complete, CX will offer 2.1 million-square-feet of state-of-the-art science and technology space, 2.4 million-square-feet of residential space that includes approximately 2,400 new units, and 100,000 square-feet of local and authentic retail for the community to enjoy. Eleven acres of activated open public and green space, including a central common, will benefit the thousands of incoming employees, residents, and neighbors adding to the vibrant and innovative East Cambridge and Kendall Square communities. The multiple modes of transportation including two MBTA lines will provide ease of access. Developed by DivcoWest and designed by a renowned team of local architects, CX buildings and the neighborhood as a whole will be LEED and WELL certified.  CX will be the second Wired Score Certified Neighborhood development in the country, providing seamless connectivity. For more information and updates, please visit, and follow along on Instagram, Facebook, LinkedIn and Twitter.